IMCS
IMCSzyme 3P (lyophilized)
IMCSzyme 3P (lyophilized)
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Overview:
IMCSzyme® 3P is a genetically modified β-glucuronidase (CAS: 9001-45-0; EC: 3.2.1.31) from E. coli supplied in lyophilized form. This enzyme is a type of hydrolase that catalyzes the cleavage of β-D-glucuronic acid from drug metabolites. This product contains a superior recombinant form of β-glucuronidase with enhanced activity.
Synonyms: β-glucuronidase, β-D-Glucuronide glucuronosohydrolase
CAS Number: 9001-45-0
PRODUCT SPECIFICATIONS:
| Physical Description: | dried film |
| Specific Activity (units*/mL): | >50,000 |
| Protein quantity: | 2 mg |
| Guaranteed Shelf Life: | 12 months** |
| Storage Temperature: | 2-8 °C |
| Purity: | > 95% based SDS PAGE |
**12 months in original package and use within 3 months of opening.
COA and Safety Information
COA and Safety Information
Posters
Posters
- SOFT 2017: Enzyme Activities (Fishman Units) Correlate Poorly with Hydrolysis Efficiencies
- SOFT 2018: Rapid Hydrolysis of Glucuronidated Opiates and Opioids in Urine Using IMCSzyme®
Find the rest of our posters on our IMCSzyme Resources page
Journal Articles
Journal Articles
- Morris AA, Chester SA, Strickland EC, McIntire GL. (2014). Rapid Enzymatic Hydrolysis Using a Novel Recombinant β-Glucuronidase in Benzodiazepine Urinalysis. Journal of Analytical Toxicology; 38(8):610-614. doi: 10.1093/jat/bku083.
- Sitasuwan P, Melendez C, Marinova M, Mastrianni K, Darragh A, Ryan E, Lee LA. (2016). Degradation of Opioids and Opiates During Acid Hydrolysis Leads to Reduced Recovery Compared to Enzymatic Hydrolysis. Journal of Analytical Toxicology; 40(8):601-607. doi: 10.1093/jat/bkw085.
- Sitasuwan P, Melendez C, Marinova M, Spruill M, Lee LA. (2019). Comparison of Purified β-glucuronidases in Patient Urine Samples Indicates a Lack of Correlation Between Enzyme Activity and Drugs of Abuse Metabolite Hydrolysis Efficiencies Leading to Potential False Negatives. Journal of Analytical Toxicology. 43(3):221-227. doi: 10.1093/jat/bky082
Find the rest of our publications on our IMCSzyme Resources page
Shipping
Shipping
- Products are shipped FedEx Priority Overnight.
- Temperature-sensitive products are shipped in specialized insulated packaging.
- All items are shipped overnight Monday through Thursday.
- We do not ship to residential addresses or P.O. Boxes.
Need Help?
Need Help?
Have questions? Email us at custserv@imcstips.com or call us at +1 (888) 560-2073. You can also fill out our contact form here.
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IMCS is an ISO 9001:2015 Certified company.
We understand the importance of being a dependable resource for our customers, which is why we've taken the necessary steps to obtain this certification. ISO 9001:2015 certifies that our procedures will meet the needs of customers and stakeholders while maintaining the highest standard of statutory and regulatory requirements pertaining to the quality system elements needed to maintain an efficient system.
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